This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.

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The Pavement Plants Citizen Science Project invites citizens to monitor plant species growing around their homes, neighborhoods, or towns. The goal is to collaboratively monitor urban flora, measuring and revealing the species richness and biodiversity of the urban ecosystem. We believe this will lead…

This dissertation revolves around the design and implementation of novel instrumentation and related measurement techniques, at the single molecule level, for use in biophysical research. Chapter 1 presents an introduction to the field of fluorescence-based single molecule measurements. In particular,…

The Great Rift Valley in Africa is a real treasure trove for discovering early human fossils. The fossils found in this part of Africa have determined our view of human evolution. But was the Great Rift Valley really the place where evolution took place or just a place where fossils are well preserved…

Many of us love music, but we don’t understand why exactly that is – or how our individual experiences of music can differ. Rebecca Schaefer will research this in the run-up to the SNAAR Festival in Utrecht. And in a unique way: students in vocational education (mbo) will be the researchers.

Members of BLRN provide a wide range of teaching on all matters of business law. The teaching ranges from courses in the Leiden Law School’s bachelor programme, including the International Business Law programme, the master programme on Company Law and the advanced master in International Civil and…

On Tuesday 14 January 2025 Milan Ismangil successfully defended a doctoral thesis and graduated.

Science and education can really flourish in an environment where everyone can be themselves and where there is room for different perspectives that bring people together from different ethnicities, genders, sexual orientations, health, religion, age and socio-economic background.

The research within the Private International Law Department covers private international law, with a particular focus on the fundamental principles of formal private international law.

Wijnhaven, Turfmarkt 99, 2511 DP, The Hague

In this article Wouter Jong and Andrea Bartolucci explore the integration of scenario-based learning (SBL) into a crisis communication course to enhance students' practical skills and reflection in real-world contexts.

The project 'Food citizens?' examines the consequences and premises of collective food procurement in three European cities (Rotterdam, Turin, and Gdańsk).

Promotor: W. Jiskoot, Co-promotor: A. Hawe

It is the aim of this project to better understand how the physical properties of lipids influences the structure and overall barrier function of the skin.

This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.

In what ways can a photographic practice act as a means to confront, or even undo, the various material properties of atmospheric enclosure that so clearly put our relationship with our environment under pressure? Is it possible to devise a set of critical and artistic strategies to comprehend the ways…

Addressing loneliness faced by students with special needs and aiming to sense the dynamics and perceptions of students during unstructured school time.

Built Environment and Domestic Material Culture in the Medieval and Post-Medieval Cyclades, Greece (13th – 20th Centuries AD)

The unit Health, Medical and Neuropsychology offers eduction and conducts research on related fields of Health, Medical and Neuropsychology.

A vibrant chronology of ceramic manufacturing practices in the valley of Juigalpa, Chontales, Nicaragua (cal 300 CE - present)

The Reading Club is a ProParte sub-club.

What issues arise in the changing landscape of privacy, identity and data protection?

Proteases degrade matrix molecules in the atherosclerotic plaque, thereby reducing atherosclerotic plaque stability. Mast cells, that contain proteases such as tryptase and chymase, have been identified at the site of rupture in specimens of human coronary arteries and their number in the plaque was…

Our current research focusses on the exploration of the Universe using the neutrino. This neutral, almost massless and only weakly interacting particle can open a window to the distant Universe and also dense regions from which photons cannot escape.

Leiden University would like to stay in contact with its alumni. That is why we try to keep contact info up to date, but we would also like to stay informed about where you are working after graduation and how your career is progressing.

The integrity and reliability of academic research are of fundamental importance to the university.

This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.

Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters

The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…

This thesis introduces a relational interaction model and a practical tool for describing, visualising and generating interactive dialogues.

Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…

Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…

Tomography is a powerful technique to non-destructively determine the interior structure of an object.Usually, a series of projection images (e.g.\ X-ray images) is acquired from a range of different positions.

Does suffering suffice? Andrei Poama, Assistant Professor at Leiden University, and Paul C. Bauer, research fellow at the Mannheim Centre for European Social Research, did an experimental assessment of desert retributivism. Their resulsts were published on April 20 on PLOS ONE.

The Leiden University Centre for the Study of Religion (LUCSoR) is part of the Leiden University Institute for Area Studies (LIAS).

Childhood sexual abuse is a common problem, with approximately one in five girls and one in 13 boys worldwide experiencing some form of sexual abuse before the age of 18. Despite its high prevalence, many individuals remain silent about these experiences, often delaying disclosure for years, with one…

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron, Co-Promotor: P. van der Putten

Throughout the year NVIC welcomes a number of guest researchers (advanced, post-MA). Read here what it takes to become one of NVIC’s guest researchers.

A New Technology-Based Firm (NTBF) is a significant enabler of job creation and a driver of the economy through stimulating innovation.

In the Psychology Lab on Wheels, we conduct innovative research together with citizens. We drive our mobile lab to people all over the country helping to bridge the gap between science and society.

Membrane proteins and membrane interactions of proteins are studied by spin label EPR. Intact, native membranes, vesicles of all sizes and nano-disks can be investigated, because the size of the object does not matter in EPR. Whereas solution NMR is limited to micelles (a few nm in diameter), by EPR…

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

On 10 October 2019, Janneke Vink defended her thesis 'The Open Society and Its Animals'. The doctoral research was supervised by Prof. P.B. Cliteur.

Promotores: Arjen Doelman, Jens Rademacher, Max Rietkerk

Bringing Dominican indigenous collections back to the community

This thesis aims at thinking through the ethical position of animals in a way that differs radically from the manner in which this ethical position is thought within contemporary animal rights discourse.