Promotor: Prof. dr. I. Snellen, Co-Promotor: Dr. M. Kenworthy

The Protein Centre can supply you with purified proteins that are essential for many experiments, ranging from in vitro inhibitor screening and enzymatic analysis to manipulation of life cells.

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

For information about the programme, please contact one of the following persons.

A deceptively simple, complicated paper

Several techniques are explored for going beyond the born-oppenheimer static surface model for molecule-surface reactions.

The Leiden University Center for Statistical Science unites the statisticians teaching and researching at Leiden University.

This article introduces the special issue on ‘Digital Activism’ by exploring some of the trends in social media activism and scholarship thereof. The authors ask to what extent this literature helps us understand Asian forms of online activism, which forms of activism have relatively done well, and…

Design and synthesis of two 3-substituted swainsonine derivatives with the aim to improve the potency and selectivity towards Golgi alpha-mannosidase II.

The Centre for Indigenous America Studies (CIAS) at Leiden University is designed to coordinate and promote the teaching and research of Indigenous languages, literatures, cultures and cultural heritage.

Digital edition of the correspondence between the philosopher Gerardus Johannes Petrus Josephus (Gerard) Bolland (1854-1922) and the philologist Pieter Jacob Cosijn (1840-1899), consisting of 46 letters covering the period 1879 to 1899.

Do you have a question about student life in Leiden, studying at Leiden University or do you want more information about the Linguistics master's programme? Chat with a current student to get answers to your questions!

The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…

The language learning resource centre unites all language teaching professionals working at Leiden University: teachers and researchers at the LUCL, ATC, LUCAS, LIAS, and ICLON. You can find a list of them, ordered by language and/or role, in the menu on the left.

The objective of this project is the development of a new psychometric model, called the Generalized Squared Distance Logistic Model (GSDLM). This model is an evolution of older psychometric approaches (such as PARELLA, GHCM, and GGUM) and the Gaussian Ordination Models (GOMs) used in environmental…

Synthetic methodlogy is described, aiding in the synthetic preparation of putative inhibitors of retaining and inverting glycosidases and glycosyl transferases. All constructs are cyclophellitol-based cyclitols.

A major challenge in the formulation of biopharmaceuticals is to overcome their inherent instability during production, storage, transportation, handling and administration. We are studying underlying mechanisms of degradation of biopharmaceuticals (including therapeutic proteins, vaccines and advanced…

The chemical synthesis of inhibitors and probes targeting endo-glycosidases.

To support interdisciplinary research on today's world-scale changes and governing challenges, the GTGC programme has awarded a number of seed grants to scholars at Leiden University collaborating across different faculties and institutes.

Leiden University also offers a small selection of research-intensive interdisciplinary courses during the winter period.

'Community Involvement in Conservation and Livelihood Initiatives in the Eastern Himalayas Reflections on Practices and Policies' is a critical reflection written by academic and societal partners included in the Futuring Heritage project consortium, published by the Integrated Mountain Initiative (IMI)…

Arabic Humanities Blog

The aim of the research described in this thesis was to use structure-based design to optimise multiple properties of aryl sulfoxide monoacylglycerol lipase inhibitors as anti-inflammatory analgesics.

How many written parliamentary questions does each party put to each minister? Political scientists Simon Otjes (University of Groningen) and Tom Louwerse (Leiden University) studied the practice in Dutch parliament and found that parties use parliamentary questions strategically as part of their ‘permanent…

Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 148-148 (2015) ISBN: 0142-5463

Lecturer at Leiden University, Mathematical Institute and Institute of Biology, Leiden - the Netherlands

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

This research cluster is a part of the Institute of Political Science’s research programme ‘Institutions, Decisions and Collective Behaviour’.

This research cluster is a part of the Institute of Political Science’s research programme ‘Institutions, Decisions and Collective Behaviour’.

This thesis describes our search to identify and understand possible regulatory mechanisms of integrin α6β4 in cell-matrix adhesion and intracelular signaling.

The legitimacy and justice of political institutions and arrangements are among the perennial and defining subjects of the field of political theory. Political theorists who participate in the research cluster ‘Legitimacy and Justice’ engage in both systematic and historical reflection on the ways legitimacy…

Thesis focused on uncovering the underlying mechanisms of the lysosomal storage disorders Gaucher's disease using chemical tools, biochemical assays and lipidomics.

Do you have a question about student life in Leiden, studying at Leiden University, or do you want more information about the History master's programme? Chat with a current student for answers to your questions!

The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology. Some of their staff members are part of the Leiden Human Evolution Collective.

The Graduate School Office of the Faculty of Science provides support to the Dean. The following staff members are part of the Graduate School of Science Office.

Yearly, the LIBC organizes a public event to share scientific research in the field of brain & cognition

On this page you can follow PhD defences by Leiden University researchers via live stream.

Members of the Business and Law Research Network have published extensively in recent years. These publications consist, among others, of books in the BLRN Book Series, the Leidse handboeken and dissertations in the E.M. Meijers Institute Series.

This thesis addresses heterogeneity in breast cancer metabolism, as well as conceptual, technological, and computational needs for integrating metabolomic and transcriptomic datasets.

Leiden Institute of Physics regularly has vacancies for staff, postdocs, and PhD positions.

Non-urban settlement organization and Roman expansion in the Roman Republic (4th-1st centuries BC)

The map application includes information from old and new buildings archaeological projects. This makes it possible to investigate whether water facilities (wells, cisterns) and waste facilities (cesspits, sewers) were the privilege of Leiden’s wealthy elite in the late 16th and 17th centuries or whether…

Here you can find the recordings of previous Florence Nightingale Colloquia.