4,303 search results for “leiden bio science paul” in the Public website
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Prison research
The Institute of Criminal Law and Criminology conducts extensive research on imprisonment. Sending a person to prison is the most severe form of punishment that can be applied in the criminal justice systems of European countries. In most countries, the number of prisoners has risen in recent decades.…
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Mapping for meaning: using concept maps to integrate clinical and basic sciences in medical education
In which way and to which extent is integration articulated in concept maps and which factors affect the resulting concept maps? By which factors is the perceived usefulness of such concept maps affected?
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RISIS – Research infrastructures for the assessment of science, technology and innovation policy
The RISIS project aims at creating a distributed research infrastructure to support and advance science and innovation studies. This will give the field a strong scientific push forward, and at the same time, provide a radically improved evidence base for research and innovation policies, for research…
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Global Health, Innovation and Society (BSc Major of Liberal Arts and Sciences: Global Challenges)
Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…
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Evert van NieuwenburgFaculty of Science
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Institute of Environmental Sciences (CML): best institute for quantitative environmental issues
A liveable planet. More biodiversity. And resources which are being managed wisely. At the CML, we want to make an impact with our research and education. On this website you can read what we do to achieve that.
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Education
BSc degrees: ‘Political Science’, ‘International Relations and Organisations’. MSc degree: Political Science, with specialisations ‘International Organisation’; ‘Dutch Politics; ‘Nationalism, Ethnic Conflict, and Development’; ‘International Politics’; ‘Political Legitimacy and Justice’; ‘Democracy…
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Princes and Prophets: Democracy and the Defamation of Power
On 1 June 2022, Tom Herrenberg defended the thesis 'Prosecutorial Discretion in International Criminal Justice'. The doctoral research was supervised by Prof. P.B. Cliteur and Prof. B.R. Rijpkema.
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Symposium on Interdisciplinary Research
On 8 November 2021 YAL organized the successful symposium Interdisciplinary Research: Challenges and Opportunities.
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Causing a stir: Radiative and mechanical feedback in starburst galaxies
Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf
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Theoterrorism v. Freedom of Speech
From Incident to Precedent
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Application and admission for students with a degree from a Dutch University of Applied Sciences (HBO)
Students with a Dutch HBO Bachelor’s in Biology and Medical Laboratory Research or equivalent can only be admitted to the master after completing the premaster’s programme.
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Mortality and HyperImage: Visual analytics techniques for biomarker discovery in massive 3D-omics datasets
Over the past decade, several novel types of spatially resolved
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Call for special sessions
We invite proposals for special sessions on interdisciplinary, under-studied, and emerging topics (deadline passed).
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Synthesis of mycobacterial phenolic glycolipids
Het proefschrift omschrijft de chemische synthese van fenolische glycolipiden van verschillende mycobacteriën met het doel om deze te kunnen gebruiken voor immunologisch onderzoek.
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Unraveling the role of signaling networks controlled by Grainyhead like transcription factor in breast cancer subtypes
This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…
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Building projects
Building projects Real Estate Department
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Design, synthesis and application of sulfur-containing heterocycles for the inhibition of glycosidases and glycosyltransferases
This thesis describes the design and synthesis of novel small molecules based on sulfur-containing heterocycles for the inhibition of glycosidases and glycosyltransferases related to Fabry and Pompe disease.
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Culture, History and Society (BA Major of Liberal Arts and Sciences: Global Challenges)
Today, globalization makes us all aware of how closely we are connected to, and often dependent upon, the actions of people who are distant from us. Human migration and economic liberalization have confronted local communities with changes happening on a global level. How can we devise ways to share…
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Faculty of Science and Technical University Denmark sign exchange agreement
The Faculty of Science of Leiden University and the Technical University of Denmark (DTU) signed an exchange agreement on Tuesday. This Erasmus+ student mobility agreement allows all students of the Faculty of Science and DTU students to follow courses at both universities from September 2017 on.
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Kristine BertheussenFaculty of Science
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Douwe BreimerFaculty of Science
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Roy StenekerFaculty of Science
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Menno HoekstraFaculty of Science
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A podium for science
Rector Magnificus Carel Stolker will retire on 8 February. If there’s one theme running through his career, it’s the links between the University and society. In this series of pre-retirement discussions, Stolker will talk one last time to people from within and without the University. This edition…
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Determining global distribution of microplastics by using citizen science
The objective of this study is to better understand the distribution of microplastics in the environment. More specifically, we will quantify the abundance and distribution of microplastics on beaches.
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LUC 101: a personalized Q&A session with a student of Liberal Arts & Sciences
Study information, LUC 101 | Information Session
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Research Design in Political Science: The new book by Dimiter Toshkov is now out
The new book by Dimiter Toshkov - associate professor of Public Administration at the Faculty of Governance and Global Affairs - has been recently published by Palgrave Macmillan.
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World Politics (BA Major of Liberal Arts and Sciences: Global Challenges)
The World Politics Major at Leiden University College The Hague examines the big ideas and the powerful forces – political, military, economic, social and cultural – that shape the world at every level, from the global to the local and everything in between. Political conflict is a key driver of many…
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International Justice (BA Major of Liberal Arts and Sciences: Global Challenges)
Home to the International Court of Justice and the International Criminal Court, The Hague is the perfect backdrop to explore conceptions of justice in our global society. Questions of human rights, peace, security and the environment present legal and policy challenges for governmental and non-governmental…
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What does the Leiden economy of the future look like?
With the long lockdown, it’s been a hard year for Leiden businesses. How can the local economy bounce back and how can the University help? Two talk shows discussing this were recently recorded in the Academy Building. They will be aired on Unity TV on 28 September and 12 October.
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New Science assessor cares for mental health students
More attention for internationalisation, diversity, but also the mental health of students: that’s what Marleen van Dorst would like to see change. As of 1 September, she will be the new assessor of the Faculty of Science.
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Inhibitors and probes targeting mannanases
This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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Chemical tools to monitor and control human proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Activity-Based Proteasome Profiling
Promotor: H.S. Overkleeft, Co-promotor: B.I. Florea
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Targeting Human Proteasomes: Substrates, Inhibitors and Prodrugs
Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Synthetic, Physical and Computational Chemistry of Propeller-shaped Polycyclic Aromatic Hydrocarbons
This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…
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Modeling interactions to unravel biomarkers for disease progression and treatment response
The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets
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Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Prepare for your studies
You’ve been accepted! Leiden University looks forward to welcoming you as a new student. Your next step is to prepare for your studies. Below you can find some tips to help you get a head start as you embark on your studies at Leiden University.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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