Three at the same time: a ligation strategy combining tetrazine–norbornene cycloaddition, Staudinger–Bertozzi ligation, and copper(I)-catalyzed click reaction was used to label the three catalytic activities of the proteasome simultaneously in a single experiment. The orthogonality of the three ligation…

A high-end label: Cyclophellitol aziridine-type activity-based probes allow for ultra-sensitive visualization of mammalian β-glucosidases (GBA1, GBA2, GBA3, and LPH) as well as several non-mammalian β-glucosidases (see picture). These probes offer new ways to study β-exoglucosidases, and configurational…

PhD students at Bio-organic Synthesis are invited to present their work during the weekly Monday Morning Biosyn Talks.

Wrenching poverty, global inequality, violent political and ethnic strife, deadlocked, unresponsive or even collapsing governments, growing dissatisfaction with democracy and missed opportunities for innovation – these are merely some of the challenges of governance and development with which our programme…

The Faculty of Social and Behavioural Sciences brings together high-quality research and outstanding teaching.

Science communication is a lot more than writing a column or giving a lecture now and then. The communication itself also has to be firmly based in sound scientific research, is the message of Professor Ionica Smeets in her inaugural lecture.

The Faculty of Social and Behavioural Sciences brings together high-quality research and outstanding mono- and multidisciplinary teaching.

In this conversation-analytic study, the authors analyze conversations between researchers from different disciplines and community members to examine relationship building in real life. This is an open access article under the Creative Commons By license.

Nature and History, Towards a Hermeneutic Philospohy of Historiography of Science

The title of European City of Science was officially handed over to a delegation from Leiden in the Italian city of Trieste on 6 September. Leiden will be the science capital of Europe for the year 2022. The EuroScience Open Forum (ESOF), the largest interdisciplinary science conference in Europe, will…

From bedtime stories about mathematics to podcasts about microplastics and games on weeds: master students from the Science Communication & Society track presented the real-life products they developed during their final presentations on 20 December. Many of the products are already implemented by c…

Fifteen knowledge institutions and the Ministry of Education, Culture and Science have signed the covenant for Open Science NL. Leiden University has also joined the covenant, via the Universities of the Netherlands. This marks the start of the Dutch Research Council’s and brings the transition to open…

A liveable planet. More biodiversity. And resources which are being managed wisely. At the CML, we want to make an impact with our research and education. On this website you can read what we do to achieve that.

In which way and to which extent is integration articulated in concept maps and which factors affect the resulting concept maps? By which factors is the perceived usefulness of such concept maps affected?

The RISIS project aims at creating a distributed research infrastructure to support and advance science and innovation studies. This will give the field a strong scientific push forward, and at the same time, provide a radically improved evidence base for research and innovation policies, for research…

Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…

The Institute of Criminal Law and Criminology conducts extensive research on imprisonment. Sending a person to prison is the most severe form of punishment that can be applied in the criminal justice systems of European countries. In most countries, the number of prisoners has risen in recent decades.…

BSc degrees: ‘Political Science’, ‘International Relations and Organisations’. MSc degree: Political Science, with specialisations ‘International Organisation’; ‘Dutch Politics; ‘Nationalism, Ethnic Conflict, and Development’; ‘International Politics’; ‘Political Legitimacy and Justice’; ‘Democracy…

The university is making its campuses future-proof with measures for climate adaptation and biodiversity. You can read in the Sustainability Implementation Agenda 2023–2026 how we harvest rainwater, limit heat stress and make more room for greenery.

Over the past decade, several novel types of spatially resolved

We invite proposals for special sessions on interdisciplinary, under-studied, and emerging topics (deadline passed).

This thesis describes the design and synthesis of novel small molecules based on sulfur-containing heterocycles for the inhibition of glycosidases and glycosyltransferases related to Fabry and Pompe disease.

Het proefschrift omschrijft de chemische synthese van fenolische glycolipiden van verschillende mycobacteriën met het doel om deze te kunnen gebruiken voor immunologisch onderzoek.

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

Building projects Real Estate Department

Although bacteria are usually invisible to the naked eye, they are the silent force behind many processes in our daily lives.

Thesis focused on uncovering the underlying mechanisms of the lysosomal storage disorders Gaucher's disease using chemical tools, biochemical assays and lipidomics.

On 1 June 2022, Tom Herrenberg defended the thesis 'Prosecutorial Discretion in International Criminal Justice'. The doctoral research was supervised by Prof. P.B. Cliteur and Prof. B.R. Rijpkema.

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Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

From Incident to Precedent

On 8 November 2021 YAL organized the successful symposium Interdisciplinary Research: Challenges and Opportunities.

The colloquia Ehrenfestii take place about once every month. This lecture series has been running since 1912.

Why are professors still warning their students against dogmatism, prejudice, pedantry, and other centuries-old vices? What explains the persistence of these scholarly vices across the ages?

The Faculty of Science of Leiden University and the Technical University of Denmark (DTU) signed an exchange agreement on Tuesday. This Erasmus+ student mobility agreement allows all students of the Faculty of Science and DTU students to follow courses at both universities from September 2017 on.

Students with a Dutch HBO Bachelor’s in Biology and Medical Laboratory Research or equivalent can only be admitted to the master after completing the premaster’s programme.

Our team is committed to the study of knowledge in its broadest sense, encompassing both ideas and practices in all its historical variety. We look at what people regarded as knowledge, how they created, collected, circulated and used it, also why it mattered to them, and how all this was embedded in…