Water is all around us and is vital for all aspects of life. Studying the various compounds and life forms that inhabit natural waters lets us better understand the world around us.

Clearance is the most important pharmacokinetic parameter for drug dose selection. Pharmacokinetic information is typically first available in the adult population, and in general only limited pharmacokinetic data are available in children when drugs enter into the market. It is therefore of the utmost…

This volume contains the first edition of 66 papyri and ostraca in the collection of the Leiden Papyrological Institute.

Students use the Journalism Lab to acquire essential skills in journalism and new media.

The language learning resource centre unites all language teaching professionals working at Leiden University: teachers and researchers at the LUCL, ATC, LUCAS, LIAS, and ICLON.

Promotor: Prof.dr. T. Hankemeier, Co-promotor: R.J. Vreeken

In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.

Do you want to apply for this master’s programme at Leiden University? Find out how to apply for your programme by following the step-by step guide in the application and admission section.

Find out how to apply for Physics and Classical/Quantum Information at Leiden University by following our step-by-step guide.

Theorists have recently made substantial progress in simulating reactive molecule-metal surface scattering but still face major challenges. The grand challenge is to develop an approach that enables accurate predictive calculations of reactions involving electronically excited states with potential…

Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.

At the Young Academy Leiden, we are closely engaged with the everyday practice of scientific research and education. From this perspective, we also contribute to the wider conversation on policy. In our policy work, we aim to be an independent and constructive voice, sensitive to current developments,…

Studies in Human Evolution is a series of the Faculty of Archaeology, Leiden University and The Max Planck Institute for Evolutionary Anthropology, Leipzig.

Reputation literature has provided crucial insights about the evolution of the US regulatory state. Daniel Carpenter’s influential account painstakingly demonstrates the relevance of reputation to bureaucratic ‘power’ and to early institutional state-building in the US context. We argue that adopting…

The project is financed by SoFoKleS and is enabled in part by support from and cooperation with Utrecht University and various parties within Leiden University such as the Graduate Schools of all faculties, HRM Learning & Development and Academia in Motion.

Leiden University has much to offer, so why not come and visit? We’d like to meet you.

The Laboratory for Human Osteoarchaeoloy examines human remains and their burial context to address questions about the human past.

The probability for dissociation of molecules on metal surfaces, which often controls the rate of industrially important catalytic processes, can depend strongly on how energy is partitioned in the incident molecule. There are many example systems where the addition of vibrational energy promotes reaction…

Cyclic peptides are investigated as a platform to induce different orientations between various ligands.

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

Because of the overarching shadow of ‘the state’ in all things diplomatic, traditional diplomatic history has neglected the study of any actors in foreign relations other than state diplomats, such as ambassadors.

Un)timely Crises explores how ‘crisis’—as a narrative, concept, grammar, and experience—structures time and space. This collectively written volume extends Bakhtin’s ‘chronotope’ to challenge mobilizations of crisis within neoliberal governmentality. The book explores how contemporary crises can trigger…

Authors who would like to publish in Inter-Section are requested to fill in this form as first step in the publication process. Before this form is filled in, the contributor must have requested at least one faculty staff member to support them in the writing and submission process.

High-Tech Innovation is the ideal choice for students who aspire to build a career where science meets advanced technology and global impact. 

This is a facility where research groups or small companies can apply for space if they need to culture human or animal cells.

Twice a month researchers from the Institute of Biology Leiden invite national and international speakers for a lecture on a broad range of topics in biology. The lectures are public and held online in Kaltura.

The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.

On Wednesday 11 June 2025 Steffie van Gompel successfully defended a doctoral thesis and graduated.

Pathways of toxicity

Mesoamerican Manuscripts: New Scientific Approaches and Interpretations brings together a wide range of modern approaches to the study of pre-colonial and early colonial Mesoamerican manuscripts. This includes innovative studies of materiality through the application of non-invasive spectroscopy and…

On Thursday 16 November 2017, Lalin Kovudhikulrungsri defended her doctoral thesis entitled ‘The Right to Travel by Air of Persons with Disabilities’. The supervisors are Professor P.M.J. Mendes de Leon and Professor A.C. Hendriks.

Single-Molecule Microscopy (SMM) techniques constitute a group of powerful imaging tools that enable researchers to study the dynamic behavior of individual molecules.

With the rise of multi-drug resistant bacterial pathogens, the possibility of a post-antibiotic world is quickly becoming reality.

Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…

One of the most intriguing papyri discovered and published in recent years is the so called

Leiden University's Pre-University Classes (PRE-Classes) are an educational programme specially designed for motivated and talented students in the final three years of secondary school.

Analysis of drug adversity

We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.

Below you can find an overview of our network.

The currently available in vitro generated human skin equivalents resemble the human skin in many aspects. However, some essential barrier characteristics do not fully mimic the native barrier. Consequently, the human skin equivalents cannot be used for screening of drugs for skin penetration.

Evolution acts via mutations in amino acid sequences. Substitution of essential amino acids leads to a nonfunctional protein. l.

This thesis investigates how non-genetic factors, such as inflammation and concomitant medication, impact hepatic drug metabolism and subsequent drug metabolizing phenotype predictions.

The Europa Institute regularly organises academic conferences, workshops, and lectures to discuss topics relevant to European law and foster cooperation and exchange between scholars working in the field.

With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.