Fifteen knowledge institutions and the Ministry of Education, Culture and Science have signed the covenant for Open Science NL. Leiden University has also joined the covenant, via the Universities of the Netherlands. This marks the start of the Dutch Research Council’s and brings the transition to open…

A liveable planet. More biodiversity. And resources which are being managed wisely. At the CML, we want to make an impact with our research and education. On this website you can read what we do to achieve that.

In which way and to which extent is integration articulated in concept maps and which factors affect the resulting concept maps? By which factors is the perceived usefulness of such concept maps affected?

The RISIS project aims at creating a distributed research infrastructure to support and advance science and innovation studies. This will give the field a strong scientific push forward, and at the same time, provide a radically improved evidence base for research and innovation policies, for research…

Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…

Lecture

The university is making its campuses future-proof with measures for climate adaptation and biodiversity. You can read in the Sustainability Implementation Agenda 2023–2026 how we harvest rainwater, limit heat stress and make more room for greenery.

The Institute of Criminal Law and Criminology conducts extensive research on imprisonment. Sending a person to prison is the most severe form of punishment that can be applied in the criminal justice systems of European countries. In most countries, the number of prisoners has risen in recent decades.…

Building projects Real Estate Department

This thesis describes the design and synthesis of novel small molecules based on sulfur-containing heterocycles for the inhibition of glycosidases and glycosyltransferases related to Fabry and Pompe disease.

We invite proposals for special sessions on interdisciplinary, under-studied, and emerging topics (deadline passed).

Over the past decade, several novel types of spatially resolved

Het proefschrift omschrijft de chemische synthese van fenolische glycolipiden van verschillende mycobacteriën met het doel om deze te kunnen gebruiken voor immunologisch onderzoek.

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

Although bacteria are usually invisible to the naked eye, they are the silent force behind many processes in our daily lives.

Thesis focused on uncovering the underlying mechanisms of the lysosomal storage disorders Gaucher's disease using chemical tools, biochemical assays and lipidomics.

BSc degrees: ‘Political Science’, ‘International Relations and Organisations’. MSc degree: Political Science, with specialisations ‘International Organisation’; ‘Dutch Politics; ‘Nationalism, Ethnic Conflict, and Development’; ‘International Politics’; ‘Political Legitimacy and Justice’; ‘Democracy…

Today, globalization makes us all aware of how closely we are connected to, and often dependent upon, the actions of people who are distant from us. Human migration and economic liberalization have confronted local communities with changes happening on a global level. How can we devise ways to share…

Wrenching poverty, global inequality, violent political and ethnic strife, deadlocked, unresponsive or even collapsing governments, growing dissatisfaction with democracy and missed opportunities for innovation – these are merely some of the challenges of governance and development with which our programme…

The Faculty of Science of Leiden University and the Technical University of Denmark (DTU) signed an exchange agreement on Tuesday. This Erasmus+ student mobility agreement allows all students of the Faculty of Science and DTU students to follow courses at both universities from September 2017 on.

The Around the Rapenburg walk takes you along the canal where Leiden University was founded 450 years ago.

Students with a Dutch HBO Bachelor’s in Biology and Medical Laboratory Research or equivalent can only be admitted to the master after completing the premaster’s programme.

Our team is committed to the study of knowledge in its broadest sense, encompassing both ideas and practices in all its historical variety. We look at what people regarded as knowledge, how they created, collected, circulated and used it, also why it mattered to them, and how all this was embedded in…

Leiden University Medical Center (LUMC) and the Centre for Human Drug Research (CHDR) are taking part in the phase 2 clinical trial of Janssen Vaccines’ candidate coronavirus vaccine. The vaccine will be tested on 45 test participants in Leiden from 14 September onwards.

The objective of this study is to better understand the distribution of microplastics in the environment. More specifically, we will quantify the abundance and distribution of microplastics on beaches.

Rector Magnificus Carel Stolker will retire on 8 February. If there’s one theme running through his career, it’s the links between the University and society. In this series of pre-retirement discussions, Stolker will talk one last time to people from within and without the University. This edition…

Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

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From Incident to Precedent

On 1 June 2022, Tom Herrenberg defended the thesis 'Prosecutorial Discretion in International Criminal Justice'. The doctoral research was supervised by Prof. P.B. Cliteur and Prof. B.R. Rijpkema.

The colloquia Ehrenfestii take place about once every month. This lecture series has been running since 1912.

Why are professors still warning their students against dogmatism, prejudice, pedantry, and other centuries-old vices? What explains the persistence of these scholarly vices across the ages?

On 8 November 2021 YAL organized the successful symposium Interdisciplinary Research: Challenges and Opportunities.

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…

Promotor: H.S. Overkleeft, Co-promotor: B.I. Florea

You’ve been accepted! Leiden University looks forward to welcoming you as a new student. Your next step is to prepare for your studies. Below you can find some tips to help you get a head start as you embark on your studies at Leiden University.

The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets

Can Cyanobacteria be engineered to convert the greenhouse gas carbon dioxide into the valuable chemical isoprene?

Leiden University offers you several services related to career orientation and job application skills.