How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

Which genes are involved in woodiness and associated traits such as drought tolerance, flowering time, stem elongation, life span, and plant herbivory, and how do these gene regulatory pathways overlap?

The aim of the research project is to get insight in the biostratigraphical age and the palaeoecological setting of the Schöningen sites and hominin behavior and subsistence during the late Lower Palaeolithic.

This PhD subproject concentrates on 16th-century ichthyology and takes Gessner’s Historia piscium (1558) (further HP) as its point of departure and focus.

In what ways and to what ends did Parisian buildings overwhelm the early modern public? This study is concerned with the experience of the sublime in architecture in seventeenth-century Paris.

This project is aimed at 1) elucidating the role of attention in itch and pain, including orientation, and attentional disengagement (i.e., directing attention away) from itch and pain; and 2) modifiability of these attentional processes.

Archiving Medieval and Post-Medieval Archaeological Fieldwork Data from the Eastern Mediterranean (600-2000)

Having encountered a series of shocks that pose an existential threat to our livelihoods, our societies have become increasingly polarized.

To what extent are, can, and should, human trafficking and human smuggling be(ing) seen as interlinked phenomena? What are the consequences of seeing the phenomena as either distinct or interlinked for the way in which migrants crossing intra-Schengen borders are treated.

Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…

In early medieval England, there was an interest in the history of the Roman Empire and kings adopted such imperial titles as 'imperator' or 'basileus'. How can we explain this interest and what functions did imperial ideas and the reception of the classical world serve in early medieval England?

Students in EFL (English as a foreign language) classes may regard their non-native teachers as successful models of intercultural communication and mediators between the cultures of English-speaking countries (ES cultures) and their own cultures. Teachers who are aware of such roles may introduce and…

Managing Diversity: Supervising Functions in Managing Colonial Workplaces

Democracy in Action is a Horizon Europe-funded initiative exploring how grassroots movements, cultural spaces, and digital innovations can strengthen democratic participation. With a special focus on youth, women, ethnic minorities and night culture, we bring together researchers, grassroots movements,…

How do the starchy botanical foodways reflect upon previous archaeological understandings in the northern and circum-Caribbean?

What does the excavated material tell us about the continuation and/or change of urban life during the transitional phrases from Antiquity to the Middle Ages on Crete and in the eastern Mediterranean more generally?

Many stimulating philosophical analyses have been written on contemporary technology; this book examines on the contrary how changes in contemporary technological environment have been reflected onto philosophy itself. The book shows how technological changes have marked a number of key concepts of…

What motivates learners in bilingual education to learn English and how can and do teaching practices contribute to that motivation?

Promotor: P.M. Brakefield

This project sets out to map, document and analyze instances of squatting in Leiden from 1970 to 1990, in order to set up an online Digital Archive of Squatting in Leiden. This archive will function as an online resource for academic research, as well as a starting point for public activities such as…

The nanoscale structure of a catalyst under reaction conditions determines its activity, selectivity, and stability. For the production of sustainable energy and materials, new catalysts are needed. By understanding the structure-activity relationships of catalysts under reaction conditions, insight…

An Investigation into the role of copper-alloy craft production in the early medieval economy of northwest Europe.

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

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Doctoral research on recent developments in museological practices by “critical” curators, interventionist artists, and personnel initiatives, focusing on ‘queering’ as an entrance point to broader intersectional issues; resulting in a report on the ‘Queer Baseline’ (to be launched in 2020), a popular…

Terrorism experts Daan Weggemans (Leiden University) and Beatrice de Graaf (Utrecht University) conducted one of the first scientific studies on the societal reintegration of jihadist former detainees. They showed that the reintegration process isn't without problems. Their conlusions are presented…

At the heart of this study is a thorough inquiry of categorisations of social identity used in the VOC’s record-keeping bureaucracy. How were service, occupational and caste groups classified and shaped by the VOC?

How did colonial law work to turn people into property? This project argues that colonial ideas about households and domestic authority were critical to legal processes of enslavement in the early modern Dutch empire. Using colonial court records from Dutch Brazil, Suriname, and the Moluccas, the project…

What impact does ethnic profiling and accusations of ethnic profiling have on organisations and the border police officers working at the operational level, and what structural factors on the societal and organisational level contribute to the process of ethnic profiling? Over a period of three years…

Promoting academic equity for students with ADHD through evidence-based accommodations and inclusive teaching methods in higher education.

How can the law provide legal safeguards for the save introduction of quantum technology for consumers, and how can these safeguards be examined and interpreted through interdisciplinary collaboration?

In this thesis we use state-of-the-art observations and simulations to provide the best constraints to date on the HVS ejection rate and constraints on the stellar content and dynamics at the GC, including the progenitor binary populations and their star formation history.

The Microscopy Unit houses, maintains and coordinates most of the microscopy equipment of the IBL. The available equipment ranges from conventional light and fluorescence microscopes, to confocal laser scanning and electron microscopes. In addition, infrastructure is available for histology, including…

The leading argument of this doctoral thesis is that Aristotle’s text De Interpretatione is of methodical relevance for present-day philosophical thinking. In the era of science and technology, the status of philosophy has become problematic.

The coastal site of Butrint is situated on a peninsula in south-western Albania, opposite the island of Corfu and Apulia in southern Italy (across the Adriatic Sea). In Medieval times, Butrint served as a connecting bridge between East and West – between Byzantium and the Latin world.

The acquisition and administration of the possessions of the “Teutonic House” in Utrecht, and its dependencies, in the Middle Ages until c.1600.

How can we understand the material instability of photographic (mixed media) artworks (1960s - present) from an integrated approach of Art History, Conservation Science and Chemistry in order to preserve these works for the future?

This long term project in Jordan is at the basis of many specialists’ studies and has several off-shoot projects. The project, with its many approaches, is also a framework for much teaching in Levantine Archaeology at Leiden University, especially concerning fieldwork methods, artefact studies, research…

How can wide-scale applications of isotope analyses and isotope mapping contribute to the identification of ancient migrants and their origins in the Western Caribbean? Can we observe linkages between individual behaviors and long-term patterns, for example as manifested in continuous waves of migration?…

Researcher: Hieke Huistra MSc. This PhD-project is directed at the historical and educational import of the Leiden University nineteenth-century pathological collections.

How and why governments engage with civil society as well as how civil society organizes itself and exerts political influence constitute the key focus of the research programme Public Governance & Civil Society. As such, this research programme offers unique expertise within the field of public administration…

Neuroimaging research has greatly advanced our insights on how the brain is organized. Now is the time for the next step: Imagine what would be possible when we cannot only map brain-functioning, but use neuroimaging to voluntarily regulate brain-activity!

What are the characteristics of impactful education for student application of inclusive design principles in design and technology programs?

China is a one-party regime, yet elections are held for the local congresses. PhD candidate Wang Zhongyuan investigated how the Communist Party uses this democratic instrument to strengthen the authoritarian regime. PhD defence 31 January.

A linguistic reconstruction of the migration of the Tocharians from Europe to China

What are the institutional dynamics of the adoption of internal market legislation?