In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

This project investigates the globalization and cultural mediation of palliative care practices, policies and discourses.

On the following page you can find an overview of all courses provided by the Department of Economics.

We offer a broad and diverse amount of courses. Below, you will find all the information about the courses offered by the Department of Business Sciences. If you click on a course, you will be redirected to the course guide.

Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price

In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.

On the 12th of November, Xander Vertegaal successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Xander on this achievement!

This research cluster explores processes of cultural creation, reception and transformation within a wide range of societal contexts from the early Middle Ages until c. 1800.

What is the cost of visual complexity? This dissertation sets out to determine the effect of the complexity of word formation on the legibility of Arabic and the role that vocalization plays in reading.

This thesis attempts to establish a dialogue between the modern and the medieval traditions in logic, by means of ‘translations’ of the medieval logical theories into the modern framework of symbolic logic, i.e. formalizations.

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

This article presents two related arguments. First, the limits of doctrinal analysis cut deeper than many EU lawyers realise. Most would probably accept that legal doctrine does not determine every legal dispute, but lawyers studying EU institutional balance often still assume that it can be deduced…

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

What would a university be without its students? In 2025, we will celebrate 450 years of studying with an exhibition showcasing our students from the past centuries. How did they study in the past? And how do they study now? This outdoor exhibition will be on display from 23 April at the Hortus bota…

Promotores: J. Kok, M. Chaudron (Chalmers University)

The making of sacrifices seems part and parcel of any elite sportsperson’s life. Remarkably, the insights that we find in the current literature in social sport studies are not able to make sense of the references to sacrifice in the data that emerged in the context of this study on the social significance…

Promotor: Prof.dr. A.G.G.M. Tielens, Co-Promotor: J.B.R. Oonk

Can we predict fluctuations in suicidal ideation in a person’s daily life, from hour to hour?

Promotor: Prof.dr. E.F. Smets

Yi-Wen Cheng defended her thesis on 28 May 2015

The project seeks to explore the interplay of valuation and inequalities in science, using the interdisciplinary and planet-critical field of forest research as empirical case. It examines which/whose knowledge is recognised on what grounds, and how social dimensions like gender and geographical location…

The bachelor’s programme in Dutch Studies marked its fortieth anniversary on 22 May with a festive gathering in Leiden.

Promotor: Prof.dr. R.M.H. Merks

The aim of this study is to further develop the Open Science Monitor, which started as a pilot study.

What makes a good historian? When historians raise this question, as they have done for centuries, they often do so to highlight that certain personal attitudes or dispositions are indispensable or studying the past. Yet their vieuws on what virtues, skills or competencies historians need most differ…

The subjects of the texts vary from Demosthenes to the delivery of camels in early Islamic Egypt, and their provenances stretch from the Eastern to the Western Desert, and from the Egyptian Nile valley to Qasr Ibrim in northern Nubia.

This PhD project investigates specific types of allusions used by Russian native speakers, namely references to classical Russian literature. The research includes the analysis of 1) how native speakers use allusions, 2) what type of discourse allusions are frequently used, and 3) how we can implement…

Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

Tero Alstola defended his thesis on 21 December 2017

In this article, Lianne Visser contributed to the understanding of why collaborative governance is a challenging response to wicked problems.

This thesis advances our understanding of lipid uptake, a vital first step in lipid metabolism, by developing innovative click chemistry-based tools to study how immune cells internalize lipids.

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

Labour is back as a significant social and political force in Indonesia, as was shown in the recent 1 May trade union demonstrations in Jakarta. Over the past years major changes have taken place in Indonesian labour law, leading to new forms of judicial and political resolution of labour disputes.