Embracing the Provinces is a collection of essays focused on people and their daily lives living in the Roman provinces, c. 27 BC-AD 476. It offers an overview of current research on Roman provinces and frontiers, deconstructing some long-held preconceptions and providing refreshing insights into unexplored…

“Transitional justice” is a field of practice, policy and study that focuses on the ways that societies respond to legacies of large-scale atrocities though tribunals, truth commissions, reparations, and other mechanisms.

The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.

CurveBend project aims to study the restauration of biodiversity in livestock landscapes through collective action, practical solutions, and research on ecological knowledge co-creation.

The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…

A full overview of THEOR PhD theses.

The Great Rift Valley in Africa is a real treasure trove for discovering early human fossils. The fossils found in this part of Africa have determined our view of human evolution. But was the Great Rift Valley really the place where evolution took place or just a place where fossils are well preserved…

Discover the origins and organization of palliative care in various institutions through Natashe Lemos Dekker's 2023 article in The Open Encyclopedia of Anthropology. Explore the connection between palliative care and a

This volume provides one of the most comprehensive overviews of the archaeology of a single Caribbean island yet published. Drawing together scholars from the Caribbean, north America and Europe, all working from a range of disciplines within the broader scope of archaeology, and drawing upon recent…

This Conference volume unites a wide range of scholars working in the fields of history, archaeology, religion, art, and philology in an effort to explore new perspec-tives and methods in the study of primary sources from premodern South and Southeast Asia.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Global Transformations and Governance Challenges (GTGC) at Leiden University aims to advance knowledge and practice on how we govern – and could govern – major world-scale changes in contemporary society. These global transformations include hegemonic and other geopolitical shifts, ecological changes,…

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…

The division of BioTherapeutics consists of the former divisions Biopharmaceutics and Drug Delivery Technology.

Archaeological research of coastal farming communities on the southern North Sea coast, 2000-800 BC

The head of MCS is also Director of the Leiden-based LDE Centre for Global Heritage and Development, President of LeidenGlobal, and staff member of the Heritage and Museums department of the Faculty of Archaeology. Joint activities are being developed at the interface between heritage and museum stu…

Doctoral Thesis

The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.

Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.

Activity-based protein profiling (ABPP) is a functional proteomics technique for directly monitoring the expression of active enzymes in cell extracts and living cells. The technique relies on irreversible inhibitors equipped with reactive groups (warheads) that covalently attach to the active site…

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

The study at hand focuses on the control of sex and youngsters through the response by authorities most notably from within criminal justice.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

Estudio arqueológico de la primera ciudad española en la Tierra Firme de América: Santa María de la Antigua del Darién

Trajectories of social life in the yucayeque (community) of El Cabo, Higüey, Dominican Republic, AD 800 to 1504

Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.

The AT-Hook Nuclear Localized 15 (AHL15) gene belongs to a plant-specific gene family of DNA-binding proteins. Overexpression of AHL15 in Arabidopsis thaliana delays developmental phase transitions whereas its loss of function causes a slight acceleration.

Spaanse Water

NNMT wordt beschouwd als een nieuw potentieel farmacologisch doelwit in de behandeling van een verscheidenheid van kankers, stofwisselingsziekten en andere pathologieën. Het toenemend aantal publicaties waarin de rol van NNMT bij ziekten wordt opgehelderd, heeft op zijn beurt de ontwikkeling van krachtige…

Current status and future prospects

Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.

Special Issue in: Visual Anthropology, Volume 29, Issue 3, 2016

This publication brings together two contributions born of different intentions but which are both dedicated to Hellenistic pottery of the Alexandria region.

We prepare you for your career. We will provide you with knowledge and professional skills to navigate the complex world of digital technologies.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Bioarchaeology covers the study of all biological remains from archaeological sites.

Mari Nakamura defended her thesis on 14 March 2017

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Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

The funerary textile tradition from the Osmore Valley, South Peru, and its social-political implications (2005)

Through extensive archaeological and documentary research, this study aims to provide a detailed analysis of the maritime cultural landscape of St. Eustatius over the past four centuries. It focuses on bridging the gap between the marine and terrestrial worlds and demonstrates that in order to truly…

This research combines archaeological, archaeometric and ethnohistorical research to study the organisation of settlement space and residence rules among the Taino Indians during the Late Ceramic Age (AD 1000-1492).

FIJI is one of the most used image analysis tools in the world. FIJI stands for FIJI is just ImageJ, it is however much more.

We highly advise you to register with a GP in Leiden or The Hague before arrival or soon after you get here.

Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…

The thesis explores micromammal fossils from the Afşar section in Anatolia, a crucial locality for understanding the Pliocene epoch and the transition to the Villafranchian Age.

This collection of papers was compiled in celebration of the remarkable academic career of Professor Wil Roebroeks, who has established himself as one of Europe’s leading figures in Palaeolithic archaeology over the past three decades and founded the Human origins research group at Leiden University…