The first book ever on information-theoretically secure multiparty computation

This thesis is about cosmological inflation and its relation to observations.

The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.

Working for a top faculty? Discover the vacancies at the Faculty of Science and apply immediately.

Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

This thesis contributes to studying primordial cosmology theories and their detectability in future observations.

Many important and extraordinary discoveries have been made in Leiden. Roam the city and discover the fascinating stories behind them. All you need is your smartphone!

A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

On Thursday 9 november, Reijer Passchier defended his dissertation 'Informal constitutional change'. His supervisor is Professor Wim Voermans.

Our research examines mental health risk and resilience in young people. We do so by integrating cultural, social, cognitive and neurobiological factors and their interactions.

Leiden University celebrated its 444th anniversary with a historical procession on 8 February. It celebrated this year’s Dies Natalis in time-honoured fashion with a ceremony in the Pieterskerk, but broke with tradition by sending professors out to primary schools.

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Children with autism spectrum disorder experience serious challenges in social functioning, which threatens their development in many areas of functioning.

The symposium is open to all registered participants and consists of a one-day programme and a poster session.

This article devises a framework to assess the degree to which human rights bodies provide duplicating or contradicting recommendations to States. Focusing on the case of torture, it creates an original database of recommendations delivered to 14 countries in the years 2012–2016. Results show that duplications…

During the early modern period, many medieval manuscripts were cut up into strips of parchment which were reused to reinforce the bindings of newly printed books. Until recently, these reused pieces of medieval manuscripts only came to light when the early modern book binding was damaged and/or subjected…

Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander

How do plant defense genes get activated?

Which adolescents are more at risk of developing social anxiety disorder later in life?

Eleven researchers from Leiden University have been awarded an Open Competition Domain Science ENW XS grant by the Dutch Research Council for their research projects. They are researching how to make software faster and greener, improve cancer detection and reduce anxiety by manipulating the biological…

The effects of many treatments are determined, to a significant degree, by factors other than the medicine or treatment itself. For example, placebo effects can be equal to the effect size of for example antidepressants or painkillers. Contributing factors are the trust placed in the doctor, the expectation…

Open online education has become a highly popular method of education. The current project aims to further our knowledge of how open online courses can be best designed to be consistent with human learning mechanics and facilitate meaningful learning.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Research in the group Clinical Neurodevelopmental Sciences is focused on understanding and influencing developmental mechanisms in children and adolescents.

Miriam Cohen defended her PhD dissertation entitled “Reparations for International Crimes and the development of a Civil Dimension of International Criminal Justice” on 28 June 2017. She wrote her thesis under the supervision of Professor L.J. van den Herik and Professor C. Stahn.

In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…

Source: PLoS ONE, Volume 10, Issue 3 (2015)

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

‘Schiedsgerichte in den Aussenverträgen der EU. Neue Entwicklungen unter Einbezug der institutionellen Verhandlungen Schweiz–EU’, Jusletter 28 May 2018

Aluminium-based adjuvants, such as aluminium hydroxide and aluminium phosphate, are well-known for their immune-stimulating properties.

The research groups within the biological, soft and complex systems research area study the physics of a broad range of biological and soft materials. This spans both experimental and theoretical research.

The dissociative chemisorption of a molecule on a transition metal surface represents a rate-limiting step in many heterogeneously catalyzed processes, whereby most chemicals are made. In spite of the importance of this reaction, an accurate first principles approach to modeling it does not yet exist.…

From a meaningless block of plastic to an advanced component that contributes to the energy transition. The technicians and scientists of our faculty think it out in detail and make it a reality. This special project shows that they need each other.

By carrying out fundamental research and providing excellent education, universities become a breeding ground for innovation and entrepreneurship.

The programme will give you the opportunity to choose from a broad range of topics to study. You will be part of an international multidisciplinary research team at our institute.

Leiden Institute of Advanced Computer Science (LIACS)

Science is under pressure and ‘alternative facts’ are increasingly being taken as truth. On 22 April, scientists will let their voices be heard on Museumplein in Amsterdam, for anyone with a passion for science. Zsuzsika Sjoerds is co-organiser of this March for Science and explains why knowledge is…

Did he dare take a gamble with his PhD research? Jeroen Methorst didn’t have to think long about it. It could fail or turn out very well. The latter is the case. Methorst developed a computer system that helps researchers find the protein they need. ‘Our whole group is now using this program.’ Methorst…

It’s about much more than learning how to write a readable piece or give a presentation that doesn’t send the audience to sleep. The intensive Science Communication Summer School gives young scientists the chance to really make contact with the public.

Annette Righolt, Honours Coordinator at FGGA, and Mira Basta, Public Administration student, tell you more.

How can Ronald Mulder run his skates across an ice layer at 60 km/h? His skating blades get help from a lubricating layer of meltwater. In Leiden, physicists found this explanation to be incomplete. Theoretician Hans van Leeuwen and experimental physicist Tjerk Oosterkamp searched for a deeper answe…

Physicist Remko Fermin from Leiden University was awarded a Rubicon grant from NWO. He will use it to study superconducting diodes that could contribute to reducing the CO2 emission of data centres.